PROMEMO - CENTER FOR PROTEINS IN MEMORY

Studying fundamental traits of learning and memory in healthy and diseased brains
A Danish National Research Foundation Center of Excellence

About PROMEMO

PROMEMO aims to identify and understand the function of memory-associated proteins that determines the persistence of a memory.

The PROMEMO "power button"

Switching memory "on" and "off" - generation and removal of an associative memory by changing synaptic strength (inducing LTD and LTP).

Approach & Methodologies

Spanning cutting-edge techniques in proteomics, complex structural biology, optogenetic memory engineering, electrophysiology, and high-resolution brain imaging.

News

A graphical summary of this study. Fear conditioning induces long-term GABAergic synaptic plasticity and activates a small population of GABAergic neurons (inhibitory engram) in the mouse central lateral amygdala (CeL). Silencing this CeL GABAergic engram disinhibits the activity of targeted extra-amygdaloid areas, selectively increasing the expression of fear during memory retrieval.

04 September 2024 - Research

PROMEMO researchers Wen-Hsien Hou and late Marco Capogna (et al.) have published the article "Inhibitory fear memory engram in the mouse central…

22 August 2024 - Dandrite

Researchers at Aarhus University are the first to identify the specific cell group in the brain that plays a central role in our ability to…

15 August 2024 - People news

André Walter starts the 15 August as new Center Manager on a part time basis. He will help managing PROMEMO while Susanne Schousboe Sjøgaard is on a…

Events

23 Jun

19 days, Monday 23 June 2025, at 09:00 - 11 July France

This course is primarily for (pre)PhD & postdocs in neurobiology. This course will allow students to integrate theoretical and methodological concepts…